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ELECTRA-DTA: a new compound-protein binding affinity prediction model based on the contextualized sequence encoding
MOTIVATION: Drug-target binding affinity (DTA) reflects the strength of the drug-target interaction; therefore, predicting the DTA can considerably benefit drug discovery by narrowing the search space and pruning drug-target (DT) pairs with low binding affinity scores. Representation learning using...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922401/ https://www.ncbi.nlm.nih.gov/pubmed/35292100 http://dx.doi.org/10.1186/s13321-022-00591-x |