Tilorone confers robust in vitro and in vivo antiviral effects against severe fever with thrombocytopenia syndrome virus

• Tilorone dihydrochloride possesses robust anti-SFTSV activity in vitro and in vivo. • Intraperitoneal administration of tilorone leads to protection against intracranial lethal challenge of SFTSV. • The anti-SFTSV mechanism of tilorone is through stimulation of host innate immunity. • Pre-treatmen...

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Detalles Bibliográficos
Autores principales: Yang, Jingjing, Yan, Yunzheng, Dai, Qingsong, Yin, Jiye, Zhao, Lei, Li, Yuexiang, Li, Wei, Zhong, Wu, Cao, Ruiyuan, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922426/
https://www.ncbi.nlm.nih.gov/pubmed/35234618
http://dx.doi.org/10.1016/j.virs.2022.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922426/
https://www.ncbi.nlm.nih.gov/pubmed/35234618
http://dx.doi.org/10.1016/j.virs.2022.01.014

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