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Recombinant Human Lactoferrin Reduces Inflammation and Increases Fluoroquinolone Penetration to Primary Granulomas during Mycobacterial Infection of C57Bl/6 Mice

Infection with Mycobacterium tuberculosis (Mtb) results in the primary formation of a densely packed inflammatory foci that limits entry of therapeutic agents into pulmonary sites where organisms reside. No current therapeutic regimens exist that modulate host immune responses to permit increased dr...

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Detalles Bibliográficos
Autores principales: Nguyen, Thao K.T., Niaz, Zainab, Kruzel, Marian L., Actor, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922470/
https://www.ncbi.nlm.nih.gov/pubmed/35226195
http://dx.doi.org/10.1007/s00005-022-00648-7