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Recombinant Human Lactoferrin Reduces Inflammation and Increases Fluoroquinolone Penetration to Primary Granulomas during Mycobacterial Infection of C57Bl/6 Mice
Infection with Mycobacterium tuberculosis (Mtb) results in the primary formation of a densely packed inflammatory foci that limits entry of therapeutic agents into pulmonary sites where organisms reside. No current therapeutic regimens exist that modulate host immune responses to permit increased dr...
Autores principales: | Nguyen, Thao K.T., Niaz, Zainab, Kruzel, Marian L., Actor, Jeffrey K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922470/ https://www.ncbi.nlm.nih.gov/pubmed/35226195 http://dx.doi.org/10.1007/s00005-022-00648-7 |
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