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Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/β-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer

OBJECTIVE: Aberrant activation of Wnt/β-catenin signaling contributes to the maintenance of cancer stem cells and chemoresistance in colorectal cancer (CRC). Retinoic acid-induced 2 (RAI2) was proved to be a tumor suppressor in CRC in our previous report. In this study, the role of RAI2 in Wnt/β-cat...

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Detalles Bibliográficos
Autores principales: Zhang, Weitao, Kong, Lu, Zhu, Hongbin, Sun, Decong, Han, Quanli, Yan, Bin, Cui, Zhi, Zhang, Weiwei, Zhang, Shurong, Kang, Xindan, Dai, Guanghai, Qian, Niansong, Yan, Wenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922473/
https://www.ncbi.nlm.nih.gov/pubmed/35299743
http://dx.doi.org/10.3389/fonc.2022.805290