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Functional replacement of myostatin with GDF-11 in the germline of mice

BACKGROUND: Myostatin (MSTN) is a transforming growth factor-ß superfamily member that acts as a major regulator of skeletal muscle mass. GDF-11, which is highly related to MSTN, plays multiple roles during embryonic development, including regulating development of the axial skeleton, kidneys, nervo...

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Detalles Bibliográficos
Autores principales: Lee, Se-Jin, Lehar, Adam, Rydzik, Renata, Youngstrom, Daniel W., Bhasin, Shalender, Liu, Yewei, Germain-Lee, Emily L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922734/
https://www.ncbi.nlm.nih.gov/pubmed/35287700
http://dx.doi.org/10.1186/s13395-022-00290-z