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Glycogen synthase kinase GSK3α promotes tumorigenesis by activating HIF1/VEGFA signaling pathway in NSCLC tumor

BACKGROUND: Lung cancer is one of the most common cancers and the leading cause of cancer-related death. Glycogen synthase kinase-3 (GSK-3) α, a member of the glycogen synthase kinase-3 family, reportedly plays a role in tumorigenesis. However, its biological function in tumorigenesis requires deepe...

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Detalles Bibliográficos
Autores principales: Cao, Xiaonian, Wu, Wei, Wang, Dao, Sun, Wei, Lai, Senyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922767/
https://www.ncbi.nlm.nih.gov/pubmed/35292059
http://dx.doi.org/10.1186/s12964-022-00825-3