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CELF1 promotes matrix metalloproteinases gene expression at transcriptional level in lens epithelial cells

BACKGROUND: RNA binding proteins (RBPs)-mediated regulation plays important roles in many eye diseases, including the canonical RBP CELF1 in cataract. While the definite molecular regulatory mechanisms of CELF1 on cataract still remain elusive. METHODS: In this study, we overexpressed CELF1 in human...

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Detalles Bibliográficos
Autores principales: Xiao, Jun, Tian, Xin, Jin, Siyan, He, Yanhui, Song, Meijiao, Zou, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922852/
https://www.ncbi.nlm.nih.gov/pubmed/35287612
http://dx.doi.org/10.1186/s12886-022-02344-8