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Verapamil inhibits efflux pumps in Candida albicans, exhibits synergism with fluconazole, and increases survival of Galleria mellonella

The emergence of resistance requires alternative methods to treat Candida albicans infections. We evaluated efficacy of the efflux pump inhibitor (EPI) verapamil (VER) with fluconazole (FLC) against FLC-resistant (CaR) and -susceptible C. albicans (CaS). The susceptibility of both strains to VER and...

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Detalles Bibliográficos
Autores principales: Vega-Chacón, Yuliana, de Albuquerque, Maria Carolina, Pavarina, Ana Cláudia, Goldman, Gustavo Henrique, Mima, Ewerton Garcia de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923067/
https://www.ncbi.nlm.nih.gov/pubmed/33410730
http://dx.doi.org/10.1080/21505594.2020.1868814