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Verapamil inhibits efflux pumps in Candida albicans, exhibits synergism with fluconazole, and increases survival of Galleria mellonella
The emergence of resistance requires alternative methods to treat Candida albicans infections. We evaluated efficacy of the efflux pump inhibitor (EPI) verapamil (VER) with fluconazole (FLC) against FLC-resistant (CaR) and -susceptible C. albicans (CaS). The susceptibility of both strains to VER and...
Autores principales: | Vega-Chacón, Yuliana, de Albuquerque, Maria Carolina, Pavarina, Ana Cláudia, Goldman, Gustavo Henrique, Mima, Ewerton Garcia de Oliveira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923067/ https://www.ncbi.nlm.nih.gov/pubmed/33410730 http://dx.doi.org/10.1080/21505594.2020.1868814 |
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