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Safety and Immunogenicity of a 100 μg mRNA-1273 Vaccine Booster for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)

IMPORTANCE: Due to the emergence of highly transmissible SARS-CoV-2 variants, evaluation of boosters is needed. OBJECTIVES: Evaluate safety and immunogenicity of 100-μg of mRNA-1273 booster dose in adults. DESIGN: Open-label, Phase 2/3 study. SETTING: Multicenter study at 8 sites in the U.S. PARTICI...

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Detalles Bibliográficos
Autores principales: Chalkias, Spyros, Schwartz, Howard, Nestorova, Biliana, Feng, Jing, Chang, Ying, Zhou, Honghong, Dutko, Frank J., Edwards, Darin K., Montefiori, David, Pajon, Rolando, Leav, Brett, Miller, Jacqueline M., Das, Rituparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923111/
https://www.ncbi.nlm.nih.gov/pubmed/35291289
http://dx.doi.org/10.1101/2022.03.04.22271830