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Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

BACKGROUND: Cancer cells selectively promote the translation of oncogenic transcripts to stimulate cancer progression. Although growing evidence has revealed that tRNA modifications and related genes participate in this process, their roles in head and neck squamous cell carcinoma (HNSCC) remain lar...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Li, Kang, Chen, Jianwen, Wang, Xiaochen, Ling, Rongsong, Cheng, Maosheng, Chen, Zhi, Chen, Fangfang, He, Qianting, Li, Shuai, Zhang, Caihua, Jiang, Yizhou, Chen, Qianming, Wang, Anxun, Chen, Demeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923133/
https://www.ncbi.nlm.nih.gov/pubmed/35179319
http://dx.doi.org/10.1002/cac2.12273