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Maintenance of the Shigella sonnei Virulence Plasmid Is Dependent on Its Repertoire and Amino Acid Sequence of Toxin-Antitoxin Systems

Shigella sonnei is a major cause of bacillary dysentery and an increasing concern due to the spread of multidrug resistance. S. sonnei harbors pINV, an ∼210 kb plasmid that encodes a type III secretion system (T3SS), which is essential for virulence. During growth in the laboratory, avirulence arise...

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Detalles Bibliográficos
Autores principales: Martyn, Jessica E., Pilla, Giulia, Hollingshead, Sarah, Winther, Kristoffer S., Lea, Susan, McVicker, Gareth, Tang, Christoph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923223/
https://www.ncbi.nlm.nih.gov/pubmed/34978459
http://dx.doi.org/10.1128/jb.00519-21