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Phylodynamic study of the conserved RNA structure encompassing the hemagglutinin cleavage site encoding region of H5 and H7 low pathogenic avian influenza viruses

Highly pathogenic avian influenza viruses (HPAIVs) evolve from low pathogenic avian influenza viruses (LPAIVs) of the H5 and H7 subtypes. This evolution is characterized by the acquisition of a multi-basic cleavage site (MBCS) motif in the hemagglutinin (HA) that leads to an extended viral tropism a...

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Detalles Bibliográficos
Autores principales: Dupré, Gabriel, Hoede, Claire, Figueroa, Thomas, Bessière, Pierre, Bertagnoli, Stéphane, Ducatez, Mariette, Gaspin, Christine, Volmer, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923263/
https://www.ncbi.nlm.nih.gov/pubmed/35299790
http://dx.doi.org/10.1093/ve/veab093