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Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium

Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4 ( + ) fibroblasts and Dpp4 ( - ) fibroblasts. Each population exhibits unique function...

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Detalles Bibliográficos
Autores principales: Yoshitake, Ryohei, Chang, Gregory, Saeki, Kohei, Ha, Desiree, Wu, Xiwei, Wang, Jinhui, Chen, Shiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923650/
https://www.ncbi.nlm.nih.gov/pubmed/35300413
http://dx.doi.org/10.3389/fcell.2022.850568