Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling

Amino-terminal fragments from proteolytically cleaved gasdermins (GSDMs) form plasma membrane pores that enable the secretion of interleukin-1β (IL-1β) and IL-18. Excessive GSDM-mediated pore formation can compromise the integrity of the plasma membrane thereby causing the lytic inflammatory cell de...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Kai, Wang, Chun, Xiao, Jianqiu, Brodt, Michael D, Yuan, Luorongxin, Yang, Tong, Alippe, Yael, Hu, Huimin, Hao, Dingjun, Abu-Amer, Yousef, Silva, Matthew J, Shen, Jie, Mbalaviele, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923664/
https://www.ncbi.nlm.nih.gov/pubmed/35244027
http://dx.doi.org/10.7554/eLife.75753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923664/
https://www.ncbi.nlm.nih.gov/pubmed/35244027
http://dx.doi.org/10.7554/eLife.75753

Ejemplares similares