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Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling

Amino-terminal fragments from proteolytically cleaved gasdermins (GSDMs) form plasma membrane pores that enable the secretion of interleukin-1β (IL-1β) and IL-18. Excessive GSDM-mediated pore formation can compromise the integrity of the plasma membrane thereby causing the lytic inflammatory cell de...

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Detalles Bibliográficos
Autores principales:	Sun, Kai, Wang, Chun, Xiao, Jianqiu, Brodt, Michael D, Yuan, Luorongxin, Yang, Tong, Alippe, Yael, Hu, Huimin, Hao, Dingjun, Abu-Amer, Yousef, Silva, Matthew J, Shen, Jie, Mbalaviele, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923664/ https://www.ncbi.nlm.nih.gov/pubmed/35244027 http://dx.doi.org/10.7554/eLife.75753

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