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SAHA Alleviates Diarrhea-Predominant Irritable Bowel Syndrome Through Regulation of the p-STAT3/SERT/5-HT Signaling Pathway

OBJECTIVE: Irritable bowel syndrome (IBS) is characterized by abdominal pain, bloating, and stool irregularity. However, its pathophysiological mechanisms, which trigger intestinal motility disorders and diarrhea leading to diarrhea-predominant IBS (D-IBS), remain largely unknown. METHODS: In the pr...

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Detalles Bibliográficos
Autores principales: Shen, Jian, Zhang, Bimeng, Chen, Jianjie, Cheng, Jiazheng, Wang, Jiali, Zheng, Xianhui, Lan, Yu, Zhang, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923685/
https://www.ncbi.nlm.nih.gov/pubmed/35300211
http://dx.doi.org/10.2147/JIR.S331303