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Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity

BACKGROUND: Alopecia areata (AA) is an acquired hair loss disorder induced by a cell-mediated autoimmune attack against anagen hair follicles. CD27-CD70 is a receptor-ligand complex which enhances T helper and cytotoxic T cell activation, survival, and proliferation. The overstimulation of this comp...

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Detalles Bibliográficos
Autores principales: Sayed Mahmoud Marie, Radwa El-, Abd El-Fadeel, Noha M., El-Sayed Marei, Yara, Atef, Lina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923777/
https://www.ncbi.nlm.nih.gov/pubmed/35300124
http://dx.doi.org/10.1155/2022/5004642