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Clonal heterogeneity by fluorescence in situ hybridization in multiple myeloma: enhanced cytogenetic risk stratification

BACKGROUND: Multiple myeloma (MM) is a proliferation of monoclonal plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. Cytogenetic analysis is a challenge in MM because of the low mitotic activity and the rapid loss of plasma cells viability in bone marrow cu...

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Detalles Bibliográficos
Autores principales: Abdel-Qader, Hadeel Yaseen, Fouad, Dina Adel, Abuelela, Soha Ahmed, Ismail, Heba Mohamed Atif, Boshnaq, Noha Hussein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923967/
https://www.ncbi.nlm.nih.gov/pubmed/37521829
http://dx.doi.org/10.1186/s43042-022-00220-0