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A flexible, thermostable nanostructured lipid carrier platform for RNA vaccine delivery

Current RNA vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are limited by instability of both the RNA and the lipid nanoparticle delivery system, requiring storage at −20°C or −70°C and compromising universally accessible vaccine distribution. This study demonstrates t...

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Detalles Bibliográficos
Autores principales: Gerhardt, Alana, Voigt, Emily, Archer, Michelle, Reed, Sierra, Larson, Elise, Van Hoeven, Neal, Kramer, Ryan, Fox, Christopher, Casper, Corey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924030/
https://www.ncbi.nlm.nih.gov/pubmed/35308783
http://dx.doi.org/10.1016/j.omtm.2022.03.009