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Combined Single Cell Transcriptome and Surface Epitope Profiling Identifies Potential Biomarkers of Psoriatic Arthritis and Facilitates Diagnosis via Machine Learning

Early diagnosis of psoriatic arthritis (PSA) is important for successful therapeutic intervention but currently remains challenging due, in part, to the scarcity of non-invasive biomarkers. In this study, we performed single cell profiling of transcriptome and cell surface protein expression to comp...

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Detalles Bibliográficos
Autores principales: Liu, Jared, Kumar, Sugandh, Hong, Julie, Huang, Zhi-Ming, Paez, Diana, Castillo, Maria, Calvo, Maria, Chang, Hsin-Wen, Cummins, Daniel D., Chung, Mimi, Yeroushalmi, Samuel, Bartholomew, Erin, Hakimi, Marwa, Ye, Chun Jimmie, Bhutani, Tina, Matloubian, Mehrdad, Gensler, Lianne S., Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924042/
https://www.ncbi.nlm.nih.gov/pubmed/35309349
http://dx.doi.org/10.3389/fimmu.2022.835760