Evidence for investigating GSK-3 inhibitors as potential therapeutics for severe COVID-19

A key component of severe COVID-19 is a “cytokine storm” i.e., the excessive expression of unneeded cytokines. Previous studies suggest that SARS-CoV-2 proteins can induce macrophages to secrete pro-inflammatory cytokines; a process that may involve Toll-like receptors (TLRs). Glycogen synthase kina...

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Detalles Bibliográficos
Autores principales: Ghazanfari, Davoud, Courreges, Maria Cecilia, Belinski, Lydia, Bergmeier, Stephen C., McCall, Kelly D., Goetz, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924054/
https://www.ncbi.nlm.nih.gov/pubmed/35367865
http://dx.doi.org/10.1016/j.bbrc.2022.03.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924054/
https://www.ncbi.nlm.nih.gov/pubmed/35367865
http://dx.doi.org/10.1016/j.bbrc.2022.03.035

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