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Evidence for investigating GSK-3 inhibitors as potential therapeutics for severe COVID-19
A key component of severe COVID-19 is a “cytokine storm” i.e., the excessive expression of unneeded cytokines. Previous studies suggest that SARS-CoV-2 proteins can induce macrophages to secrete pro-inflammatory cytokines; a process that may involve Toll-like receptors (TLRs). Glycogen synthase kina...
Autores principales: | Ghazanfari, Davoud, Courreges, Maria Cecilia, Belinski, Lydia, Bergmeier, Stephen C., McCall, Kelly D., Goetz, Douglas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924054/ https://www.ncbi.nlm.nih.gov/pubmed/35367865 http://dx.doi.org/10.1016/j.bbrc.2022.03.035 |
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