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RAD51 is essential for spermatogenesis and male fertility in mice

The recombinase RAD51 catalyzes the DNA strand exchange reaction in homologous recombination (HR) during both mitosis and meiosis. However, the physiological role of RAD51 during spermatogenesis remains unclear since RAD51 null mutation is embryonic lethal in mice. In this study, we generated a cond...

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Detalles Bibliográficos
Autores principales: Qin, Junchao, Huang, Tao, Wang, Jing, Xu, Limei, Dang, Qianli, Xu, Xiuhua, Liu, Hongbin, Liu, Zhaojian, Shao, Changshun, Zhang, Xiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924220/
https://www.ncbi.nlm.nih.gov/pubmed/35292640
http://dx.doi.org/10.1038/s41420-022-00921-w