ARL6IP5 reduces cisplatin-resistance by suppressing DNA repair and promoting apoptosis pathways in ovarian carcinoma

Ovarian carcinoma (OC) is the most lethal gynecological malignancy due to frequent recurrence resulting from cisplatin-resistance. ARL6IP5 is a novel gene implicated to suppress cisplatin-resistance by activating apoptosis and inhibiting DNA repair through XRCC1 and PARP1. We investigated the clinic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ji-Ye, Bahar, Entaz, Lee, Jung-Yun, Chang, Sunhee, Kim, Se Hoon, Park, Eun Young, Do, Sung-Im, Yoon, Hyonok, Kim, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924236/
https://www.ncbi.nlm.nih.gov/pubmed/35293383
http://dx.doi.org/10.1038/s41419-022-04568-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924236/
https://www.ncbi.nlm.nih.gov/pubmed/35293383
http://dx.doi.org/10.1038/s41419-022-04568-4

Ejemplares similares