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ARL6IP5 reduces cisplatin-resistance by suppressing DNA repair and promoting apoptosis pathways in ovarian carcinoma

Ovarian carcinoma (OC) is the most lethal gynecological malignancy due to frequent recurrence resulting from cisplatin-resistance. ARL6IP5 is a novel gene implicated to suppress cisplatin-resistance by activating apoptosis and inhibiting DNA repair through XRCC1 and PARP1. We investigated the clinic...

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Detalles Bibliográficos
Autores principales:	Kim, Ji-Ye, Bahar, Entaz, Lee, Jung-Yun, Chang, Sunhee, Kim, Se Hoon, Park, Eun Young, Do, Sung-Im, Yoon, Hyonok, Kim, Hyun-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924236/ https://www.ncbi.nlm.nih.gov/pubmed/35293383 http://dx.doi.org/10.1038/s41419-022-04568-4

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