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Comprehensive evaluation of deconvolution methods for human brain gene expression

Transcriptome deconvolution aims to estimate the cellular composition of an RNA sample from its gene expression data, which in turn can be used to correct for composition differences across samples. The human brain is unique in its transcriptomic diversity, and comprises a complex mixture of cell-ty...

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Detalles Bibliográficos
Autores principales: Sutton, Gavin J., Poppe, Daniel, Simmons, Rebecca K., Walsh, Kieran, Nawaz, Urwah, Lister, Ryan, Gagnon-Bartsch, Johann A., Voineagu, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924248/
https://www.ncbi.nlm.nih.gov/pubmed/35292647
http://dx.doi.org/10.1038/s41467-022-28655-4