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Comprehensive evaluation of deconvolution methods for human brain gene expression
Transcriptome deconvolution aims to estimate the cellular composition of an RNA sample from its gene expression data, which in turn can be used to correct for composition differences across samples. The human brain is unique in its transcriptomic diversity, and comprises a complex mixture of cell-ty...
Autores principales: | Sutton, Gavin J., Poppe, Daniel, Simmons, Rebecca K., Walsh, Kieran, Nawaz, Urwah, Lister, Ryan, Gagnon-Bartsch, Johann A., Voineagu, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924248/ https://www.ncbi.nlm.nih.gov/pubmed/35292647 http://dx.doi.org/10.1038/s41467-022-28655-4 |
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