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Succinate Is a Natural Suppressor of Antiviral Immune Response by Targeting MAVS

Succinate is at the crossroads of multiple metabolic pathways and plays a role in several immune responses acting as an inflammation signal. However, whether succinate regulates antiviral immune response remains unclear. Here, we found that the production of succinate was reduced in RAW264.7 cells d...

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Detalles Bibliográficos
Autores principales: Xiao, Yue, Chen, Xinyi, Wang, Zhun, Quan, Jiazheng, Zhao, Xibao, Tang, Haimei, Wu, Han, Di, Qianqian, Wu, Zherui, Chen, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924363/
https://www.ncbi.nlm.nih.gov/pubmed/35309330
http://dx.doi.org/10.3389/fimmu.2022.816378