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Heat Shock Proteins and HSF1 in Cancer

Fitness of cells is dependent on protein homeostasis which is maintained by cooperative activities of protein chaperones and proteolytic machinery. Upon encountering protein-damaging conditions, cells activate the heat-shock response (HSR) which involves HSF1-mediated transcriptional upregulation of...

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Detalles Bibliográficos
Autores principales: Cyran, Anna M., Zhitkovich, Anatoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924369/
https://www.ncbi.nlm.nih.gov/pubmed/35311075
http://dx.doi.org/10.3389/fonc.2022.860320