Cargando…

Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication

Human cytomegalovirus (HCMV) replicates its DNA genome in specialized replication compartments (RCs) in the host cell nucleus. These membrane-less organelles originate as spherical structures and grow in size over time. However, the mechanism of RC biogenesis has remained understudied. Using live-ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Caragliano, Enrico, Bonazza, Stefano, Frascaroli, Giada, Tang, Jiajia, Soh, Timothy K., Grünewald, Kay, Bosse, Jens B., Brune, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924372/
https://www.ncbi.nlm.nih.gov/pubmed/35263605
http://dx.doi.org/10.1016/j.celrep.2022.110469