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Human Cerebral Perfusion, Oxygen Consumption, and Lactate Production in Response to Hypoxic Exposure

Exposure to moderate hypoxia in humans leads to cerebral lactate production, which occurs even when the cerebral metabolic rate of oxygen (CMRO(2)) is unaffected. We searched for the mechanism of this lactate production by testing the hypothesis of upregulation of cerebral glycolysis mediated by hyp...

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Detalles Bibliográficos
Autores principales: Vestergaard, Mark B, Ghanizada, Hashmat, Lindberg, Ulrich, Arngrim, Nanna, Paulson, Olaf B, Gjedde, Albert, Ashina, Messoud, Larsson, Henrik B W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924433/
https://www.ncbi.nlm.nih.gov/pubmed/34448827
http://dx.doi.org/10.1093/cercor/bhab294