Recent Advances in the Elucidation of Frataxin Biochemical Function Open Novel Perspectives for the Treatment of Friedreich’s Ataxia

Friedreich’s ataxia (FRDA) is the most prevalent autosomic recessive ataxia and is associated with a severe cardiac hypertrophy and less frequently diabetes. It is caused by mutations in the gene encoding frataxin (FXN), a small mitochondrial protein. The primary consequence is a defective expressio...

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Detalles Bibliográficos
Autores principales: Monfort, Beata, Want, Kristian, Gervason, Sylvain, D’Autréaux, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924461/
https://www.ncbi.nlm.nih.gov/pubmed/35310092
http://dx.doi.org/10.3389/fnins.2022.838335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924461/
https://www.ncbi.nlm.nih.gov/pubmed/35310092
http://dx.doi.org/10.3389/fnins.2022.838335

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