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Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis

Hyperuricemia has become a common metabolic disease, and is a risk factor for multiple diseases, including chronic kidney disease. Our recent study indicated that following persistent uric acid stimulation, autophagy was activated in rats of hyperuricemic nephropathy (HN) and facilitated the develop...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Shi, Yingfeng, Chen, Hui, Tao, Min, Zhou, Xun, Li, Jinqing, Ma, Xiaoyan, Wang, Yi, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924517/
https://www.ncbi.nlm.nih.gov/pubmed/35309342
http://dx.doi.org/10.3389/fimmu.2022.858494