QbD Supported Optimization of the Alginate-Chitosan Nanoparticles of Simvastatin in Enhancing the Anti-Proliferative Activity against Tongue Carcinoma

The goal of the current study is to develop a chitosan alginate nanoparticle system encapsulating the model drug, simvastatin (SIM-CA-NP) using a novel polyelectrolytic complexation method. The formulation was optimized using the central composite design by considering the concentrations of chitosan...

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Detalles Bibliográficos
Autores principales: Rizg, Waleed Y., Naveen, N. Raghavendra, Kurakula, Mallesh, Bukhary, Haitham A., Safhi, Awaji Y., Alfayez, Eman, Sindi, Amal M., Ali, Sarah, Murshid, Samar S., Hosny, Khaled M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924759/
https://www.ncbi.nlm.nih.gov/pubmed/35200484
http://dx.doi.org/10.3390/gels8020103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924759/
https://www.ncbi.nlm.nih.gov/pubmed/35200484
http://dx.doi.org/10.3390/gels8020103

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