Synthesis and Evaluation of a Library of Alternating Amphipathic Copolymers to Solubilize and Study Membrane Proteins

[Image: see text] Amphipathic copolymers such as poly(styrene-maleic acid) (SMA) are promising tools for the facile extraction of membrane proteins (MPs) into native nanodiscs. Here, we designed and synthesized a library of well-defined alternating copolymers of SMA analogues in order to elucidate p...

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Detalles Bibliográficos
Autores principales: Kopf, Adrian H., Lijding, Odette, Elenbaas, Barend O. W., Koorengevel, Martijn C., Dobruchowska, Justyna M., van Walree, Cornelis A., Killian, J. Antoinette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924871/
https://www.ncbi.nlm.nih.gov/pubmed/34994549
http://dx.doi.org/10.1021/acs.biomac.1c01166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924871/
https://www.ncbi.nlm.nih.gov/pubmed/34994549
http://dx.doi.org/10.1021/acs.biomac.1c01166

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