Cargando…

Synthesis and Evaluation of a Library of Alternating Amphipathic Copolymers to Solubilize and Study Membrane Proteins

[Image: see text] Amphipathic copolymers such as poly(styrene-maleic acid) (SMA) are promising tools for the facile extraction of membrane proteins (MPs) into native nanodiscs. Here, we designed and synthesized a library of well-defined alternating copolymers of SMA analogues in order to elucidate p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopf, Adrian H., Lijding, Odette, Elenbaas, Barend O. W., Koorengevel, Martijn C., Dobruchowska, Justyna M., van Walree, Cornelis A., Killian, J. Antoinette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924871/ https://www.ncbi.nlm.nih.gov/pubmed/34994549 http://dx.doi.org/10.1021/acs.biomac.1c01166

Ejemplares similares

The styrene–maleic acid copolymer: a versatile tool in membrane research
por: Dörr, Jonas M., et al.
Publicado: (2015)

Solubilization of lipids and lipid phases by the styrene–maleic acid copolymer
por: Dominguez Pardo, Juan J., et al.
Publicado: (2016)

Membrane-Catalyzed Aggregation of Islet Amyloid Polypeptide Is Dominated by Secondary Nucleation
por: Elenbaas, Barend O. W., et al.
Publicado: (2022)

An efficient expression tag library based on self-assembling amphipathic peptides
por: Zhao, Weixin, et al.
Publicado: (2019)

Controlling the Spatial Distribution of Solubilized Compounds within Copolymer Micelles
por: Ianiro, Alessandro, et al.
Publicado: (2019)

Strategic optimization of conditions for the solubilization of GST-tagged amphipathic helix-containing ciliary proteins overexpressed as inclusion bodies in E. coli
por: Shendge, Amruta A., et al.
Publicado: (2022)

Prediction of amphipathic helix—membrane interactions with Rosetta
por: Gulsevin, Alican, et al.
Publicado: (2021)

Solubilization of Membrane Proteins into Functional Lipid‐Bilayer Nanodiscs Using a Diisobutylene/Maleic Acid Copolymer
por: Oluwole, Abraham Olusegun, et al.
Publicado: (2017)

PEG–Polypeptide Block Copolymers as pH-Responsive Endosome-Solubilizing Drug Nanocarriers
por: Quadir, Mohiuddin A., et al.
Publicado: (2014)

Membrane Thinning and Thickening Induced by Membrane-Active Amphipathic Peptides
por: Grage, Stephan L., et al.
Publicado: (2016)

The Many Faces of Amphipathic Helices
por: Giménez-Andrés, Manuel, et al.
Publicado: (2018)

Phosphorus Solubilization by Bacillus Species
por: Saeid, Agnieszka, et al.
Publicado: (2018)

The synthesis of water-soluble CDM-AM copolymer by irradiation and its solubilization effect on hydrophobic drugs
por: Li, Yong-Fu, et al.
Publicado: (2018)

Chirality-Dependent Adsorption between Amphipathic Peptide and POPC Membrane
por: Chen, Ke, et al.
Publicado: (2019)

The effectiveness of styrene-maleic acid (SMA) copolymers for solubilisation of integral membrane proteins from SMA-accessible and SMA-resistant membranes
por: Swainsbury, David J.K., et al.
Publicado: (2017)

Preparation and Characterization of an Amphipathic Magnetic Nanosphere
por: Ji, Yongsheng, et al.
Publicado: (2014)

Interaction of Terminal Oxidases with Amphipathic Molecules
por: Azarkina, Natalia V., et al.
Publicado: (2023)

Structural determinants of alternating (α1 → 4) and (α1 → 6) linkage specificity in reuteransucrase of Lactobacillus reuteri
por: Meng, Xiangfeng, et al.
Publicado: (2016)

Bacterial Reaction Centers Purified with Styrene Maleic Acid Copolymer Retain Native Membrane Functional Properties and Display Enhanced Stability**
por: Swainsbury, David J K, et al.
Publicado: (2014)

Solubilization Behavior of Homopolymer in Its Blend with the Block Copolymer Displaying the Feature of Lower Critical Ordering Transition
por: Lin, Yu-Hsuan, et al.
Publicado: (2021)

Solubilization of immune precipitates by six isolated alternative pathway proteins
Publicado: (1981)

Amphipathic Polymers Enable the Study of Functional Membrane Proteins in the Gas Phase
por: Leney, Aneika C., et al.
Publicado: (2012)

Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone
por: Doucet, Christine M., et al.
Publicado: (2015)

Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains
por: Jiang, Yiping, et al.
Publicado: (2019)

An amphipathic helix enables septins to sense micrometer-scale membrane curvature
por: Cannon, Kevin S., et al.
Publicado: (2019)

Amphipathic Janus Membrane with Hierarchical Multiscale Hyperporous Structure for Interfacial Catalysis
por: Lin, Yakai, et al.
Publicado: (2020)

Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission
por: Zhukovsky, Mikhail A., et al.
Publicado: (2019)

Amphipathic Peptides Impede Lipid Domain Fusion in Phase-Separated Membranes
por: Pinigin, Konstantin V., et al.
Publicado: (2021)

Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling
por: Woods, Benjamin L., et al.
Publicado: (2021)

Facially Amphipathic Glycopolymers Inhibit Ice Recrystallization
por: Graham, Ben, et al.
Publicado: (2018)

Asymmetric effects of amphipathic molecules on mechanosensitive channels
por: Bavi, Omid, et al.
Publicado: (2022)

Membrane remodeling by the M2 amphipathic helix drives influenza virus membrane scission
por: Martyna, Agnieszka, et al.
Publicado: (2017)

Antibiotic Potential and Biophysical Characterization of Amphipathic β-Stranded [XZ](n) Peptides With Alternating Cationic and Hydrophobic Residues
por: Strandberg, Erik, et al.
Publicado: (2021)

Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains
por: Boucrot, Emmanuel, et al.
Publicado: (2012)

Essential Mycoplasma Glycolipid Synthase Adheres to the Cell Membrane by Means of an Amphipathic Helix
por: Romero-García, Javier, et al.
Publicado: (2019)

Current Developments in Native Nanometric Discoidal Membrane Bilayer Formed by Amphipathic Polymers
por: Esmaili, Mansoore, et al.
Publicado: (2021)

Two transporters cooperate to secrete amphipathic peptides from the cytoplasmic and membranous milieus
por: Dickey, Seth W., et al.
Publicado: (2023)

The Membrane-Mediated Interaction of Liquid-Ordered Lipid Domains in the Presence of Amphipathic Peptides
por: Pinigin, Konstantin V., et al.
Publicado: (2023)

Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer
por: Zhu, Lina, et al.
Publicado: (2022)

Nonionic Microemulsions as Solubilizers of Hydrophobic Drugs: Solubilization of Paclitaxel
por: Lo, Jen-Ting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bvt09d1cd3sh5tqrfvdcg39l1c