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Engineering of a synthetic antibody fragment for structural and functional studies of K(+) channels

Engineered antibody fragments (Fabs) have made major impacts on structural biology research, particularly to aid structural determination of membrane proteins. Nonetheless, Fabs generated by traditional monoclonal technology suffer from challenges of routine production and storage. Starting from the...

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Detalles Bibliográficos
Autores principales: Rohaim, Ahmed, Slezak, Tomasz, Koh, Young Hoon, Blachowicz, Lydia, Kossiakoff, Anthony A., Roux, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924934/
https://www.ncbi.nlm.nih.gov/pubmed/35234830
http://dx.doi.org/10.1085/jgp.202112965