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Engineering of a synthetic antibody fragment for structural and functional studies of K(+) channels
Engineered antibody fragments (Fabs) have made major impacts on structural biology research, particularly to aid structural determination of membrane proteins. Nonetheless, Fabs generated by traditional monoclonal technology suffer from challenges of routine production and storage. Starting from the...
Autores principales: | Rohaim, Ahmed, Slezak, Tomasz, Koh, Young Hoon, Blachowicz, Lydia, Kossiakoff, Anthony A., Roux, Benoît |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924934/ https://www.ncbi.nlm.nih.gov/pubmed/35234830 http://dx.doi.org/10.1085/jgp.202112965 |
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