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Structural principles of CRISPR-Cas enzymes used in nucleic acid detection

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-based technology has revolutionized the field of biomedicine with broad applications in genome editing, therapeutics and diagnostics. While a majority of applications involve the RNA-guided site-specific DNA or RNA cleavage by CRISPR...

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Detalles Bibliográficos
Autores principales: Das, Anuska, Goswami, Hemant N., Whyms, Charlisa T., Sridhara, Sagar, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924977/
https://www.ncbi.nlm.nih.gov/pubmed/35123001
http://dx.doi.org/10.1016/j.jsb.2022.107838