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New insights into regulation of αIIbβ3 integrin signaling by filamin A

BACKGROUND: Filamin (FLN) regulates many cell functions through its scaffolding activity cross‐linking cytoskeleton and integrins. FLN was shown to inhibit integrin activity, but the exact mechanism remains unclear. OBJECTIVES: The aim of this study was to evaluate the role of filamin A (FLNa) subdo...

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Detalles Bibliográficos
Autores principales: Lamrani, Lamia, Adam, Frédéric, Soukaseum, Christelle, Denis, Cécile V., Raslova, Hana, Rosa, Jean‐Philippe, Bryckaert, Marijke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924993/
https://www.ncbi.nlm.nih.gov/pubmed/35316942
http://dx.doi.org/10.1002/rth2.12672