Synthesis of Benzofused O- and N-Heterocycles through Cascade Carbopalladation/Cross-Alkylation of Alkynes Involving the C–C Cleavage of Cyclobutanols

[Image: see text] We report a Pd-catalyzed route to heterocycles bearing a tetrasubstituted alkene fragment. Our approach merges the intramolecular carbopalladation of tethered alkynes with an alkylation step produced by the C–C cleavage of cyclobutanol derivatives. An alkenyl-Pd(II) intermediate ha...

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Detalles Bibliográficos
Autores principales: Pérez-Gómez, Marta, Herrera-Ramírez, Piedad, Bautista, Delia, Saura-Llamas, Isabel, García-López, José-Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925021/
https://www.ncbi.nlm.nih.gov/pubmed/35308581
http://dx.doi.org/10.1021/acs.organomet.2c00015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925021/
https://www.ncbi.nlm.nih.gov/pubmed/35308581
http://dx.doi.org/10.1021/acs.organomet.2c00015

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