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Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse(1)

BACKGROUND: Probiotic supplementation reestablishes microbiome diversity and improves brain function in Alzheimer’s disease (AD); their molecular mechanisms, however, have not yet been fully illustrated. OBJECTIVE: We investigated the effects of orally supplemented Bifidobacterium breve MCC1274 on c...

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Detalles Bibliográficos
Autores principales: Abdelhamid, Mona, Zhou, Chunyu, Ohno, Kazuya, Kuhara, Tetsuya, Taslima, Ferdous, Abdullah, Mohammad, Jung, Cha-Gyun, Michikawa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925106/
https://www.ncbi.nlm.nih.gov/pubmed/34958017
http://dx.doi.org/10.3233/JAD-215025