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Efficacy and safety of onabotulinumtoxinA with standardized physiotherapy for the treatment of pediatric lower limb spasticity: A randomized, placebo-controlled, phase III clinical trial

BACKGROUND: Spasticity is common in cerebral palsy and can result in pain and diminished health-related quality of life. OBJECTIVE: To evaluate the safety and efficacy of onabotulinumtoxinA for lower limb spasticity treatment in children with cerebral palsy. METHODS: In this registrational phase 3,...

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Detalles Bibliográficos
Autores principales: Dimitrova, Rozalina, Kim, Heakyung, Meilahn, Jill, Chambers, Henry G., Racette, Brad A., Bonikowski, Marcin, Park, Eun Sook, McCusker, Emily, Liu, Chengcheng, Brin, Mitchell F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925123/
https://www.ncbi.nlm.nih.gov/pubmed/34957954
http://dx.doi.org/10.3233/NRE-210070