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Characterization of a novel HLA-A*11:335 allele resulting from a rare interlocus recombination involving HLA-A*11:01:01:01/126 and HLA-H*02:07/14/18 alleles with nanopore sequencing, in a volunteer from the China Marrow Donor Program

BACKGROUND: The major histocompatibility complex (MHC) in humans includes three classical class I loci (A, B, and C), which are important biomarkers for the transplantation of organs and hematopoietic stem cells. In the MHC, polymorphism is known to be extremely high while interlocus recombination i...

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Detalles Bibliográficos
Autores principales: Zhang, Li-Qun, Rozemuller, Erik, Wang, Dan, Liu, Xiang-Jun, Cai, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925214/
https://www.ncbi.nlm.nih.gov/pubmed/35296321
http://dx.doi.org/10.1186/s12920-022-01176-1