Downregulation of miR-211-5p Promotes Carboplatin Resistance in Human Retinoblastoma Y79 Cells by Affecting the GDNF–LIF Interaction

PURPOSE: To investigate the role of the miR-211-5p-GDNF signaling pathway in carboplatin resistance of retinoblastoma Y79 cells and what factors it may be affected by. METHODS: A carboplatin-resistant retinoblastoma cell line (Y79R) was established in vitro. RNA-seq and microRNA-seq were constructed...

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Detalles Bibliográficos
Autores principales: Ke, Ning, Chen, Lin, Liu, Qing, Xiong, Haibo, Chen, Xinke, Zhou, Xiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925320/
https://www.ncbi.nlm.nih.gov/pubmed/35311096
http://dx.doi.org/10.3389/fonc.2022.848733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925320/
https://www.ncbi.nlm.nih.gov/pubmed/35311096
http://dx.doi.org/10.3389/fonc.2022.848733

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