Exposure of α-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease

The accumulation of proteinaceous deposits comprised largely of the α-synuclein protein is one of the main hallmarks of Parkinson's disease (PD) and related synucleinopathies. Their progressive development coincides with site-specific phosphorylation, oxidative stress and eventually, compromise...

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Detalles Bibliográficos
Autores principales: Moudio, Serge, Rodin, Fredrik, Albargothy, Nazira Jamal, Karlsson, Urban, Reyes, Juan F., Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925863/
https://www.ncbi.nlm.nih.gov/pubmed/35309552
http://dx.doi.org/10.3389/fneur.2022.826102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925863/
https://www.ncbi.nlm.nih.gov/pubmed/35309552
http://dx.doi.org/10.3389/fneur.2022.826102

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