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Psychosis in Alzheimer's Disease Is Associated With Increased Excitatory Neuron Vulnerability and Post-transcriptional Mechanisms Altering Synaptic Protein Levels

Alzheimer's disease with psychosis (AD+P) is a heritable phenotypic variant of the disease which is associated with more rapid cognitive deterioration compared to Alzheimer's disease without psychosis (AD–P). Cognitive decline in AD correlates with synapse loss, and our previous studies su...

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Detalles Bibliográficos
Autores principales: DeChellis-Marks, Michael R., Wei, Yue, Ding, Ying, Wolfe, Cody M., Krivinko, Joshua M., MacDonald, Matthew L., Lopez, Oscar L., Sweet, Robert A., Kofler, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925864/
https://www.ncbi.nlm.nih.gov/pubmed/35309563
http://dx.doi.org/10.3389/fneur.2022.778419