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The PIWI/piRNA response is relaxed in a rodent that lacks mobilizing transposable elements

Transposable elements (TEs) are genomic parasites that can propagate throughout host genomes. Mammalian genomes are typically dominated by LINE retrotransposons and their associated SINEs, and germline mobilization is a challenge to genome integrity. There are defenses against TE proliferation and t...

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Detalles Bibliográficos
Autores principales: Vandewege, Michael W., Patt, Roy N., Merriman, Dana K., Ray, David A., Hoffmann, Federico G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8925971/
https://www.ncbi.nlm.nih.gov/pubmed/35064043
http://dx.doi.org/10.1261/rna.078862.121